Gyre Therapeutics to Present Promising Phase 3 Results for Liver Fibrosis Treatment at Major Medical Conference

Gyre Therapeutics Announces Phase 3 Results for Liver Fibrosis Treatment at The Liver Meeting® 2025

Gyre Therapeutics (Nasdaq: GYRE), a leading biopharmaceutical company known for its commitment to developing advanced therapies targeting fibrosis, revealed that it will present results from its successful Phase 3 clinical trial evaluating Hydronidone. Hydronidone is a novel anti-fibrotic agent designed to inhibit the activation of hepatic stellate cells (HSCs) and encourage their apoptosis, making it a promising candidate for treating liver fibrosis in patients with chronic hepatitis B.

The findings will be featured at The Liver Meeting® 2025, hosted by the American Association for the Study of Liver Diseases (AASLD), held in Washington, D.C., from November 7 to 10, 2025. The study results have earned the distinction of being selected for the prestigious Poster of Distinction category.

Presentation Details

  • Session Title: Phase 3 Trial of Hydronidone for Liver Fibrosis in Chronic Hepatitis B
  • Presenting Author: Prof. Lungen Lu, M.D., Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
  • Session: Hepatitis B
  • Date/Time: Friday, November 7, 2025, 8:00 a.m. – 5:00 p.m. Eastern Time
  • Publication Number: 1121

About Gyre Therapeutics

Based in San Diego, Gyre Therapeutics primarily focuses on developing and commercializing Hydronidone for treating liver fibrosis, including conditions like MASH (metabolic dysfunction-associated steatohepatitis), in the United States. The company leverages its expertise in preclinical and clinical research, using MASH rodent models and studies involving chronic hepatitis B-induced liver fibrosis. Internationally, particularly in China, Gyre Therapeutics is also developing additional treatments such as ETUARY®, F573, F528, and F230 through Gyre Pharmaceuticals, a company in which it holds an indirect controlling interest.

Continued corporation investment in innovative biopharmaceutical research underscores Gyre’s commitment to tackling complex chronic diseases.


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